Uricase(UA-R) e tsoang ho Microorganism
Tlhaloso
Enzyme ena e na le thuso bakeng sa enzymatic determi nation ea uric acid tlhahlobo ea bongaka.Uricase e kenya letsoho ho catabolism ea purine.E susumetsa phetoho ea uric acid e sa qhibiliheng haholo ho ba 5-hydroxyisourate.Ho bokellana ha uric acid ho baka tšenyo ea sebete / liphio kapa ho baka gout ka nako e telele.Ho litoeba, phetoho ea liphatsa tsa lefutso tsa uricase e baka keketseho ea tšohanyetso ea uric acid.Litoeba, tse haelloang ke lefutso lena, li bontša hyperuricemia, hyperuricosuria, le uric acid crystalline obstructive nephropathy.
Sebopeho sa Lik'hemik'hale
Molao-motheo oa ho itšoara
Uric acid + O2+2H2O→ Allantoin + CO2+ H2O2
Tlhaloso
| Lintho tsa Tlhahlobo | Litlhaloso |
| Tlhaloso | White amorphous phofo, lyophilized |
| Ketsahalo | ≥20U/mg |
| Bohloeki(SDS-PAGE) | ≥90% |
| Solubility(10mg phofo/ml) | Hlakileng |
| Ho kopanya li-enzyme | |
| NADH/NADPH oxidase | ≤0.01% |
| Catalase | ≤0.03% |
Lipalangoang le polokelo
Lipalangoang:E romelloa ka tlas'a -20°C
Polokelo :Boloka ho -20°C(Nako e telele), 2-8°C(Nako e khutšoanyane)
E khothaletsoa tlhahlobo hapeBophelo:2 lilemo
lihlahisoa tse amanang
Ngola molaetsa wa hao mona mme o re romele wona
