Fructosyl-peptide Oxidase (FPOX)
Tlhaloso
Enzyme e na le thuso bakeng sa qeto ea fructosyl-peptide le fructosyl-L-amino acid.
Sebopeho sa Lik'hemik'hale
Molao-motheo oa ho itšoara
Fructosyl-peptide + H2O + O2→ Peptide + Glucosone + H2O2
Tlhaloso
Lintho tsa Tlhahlobo | Litlhaloso |
Tlhaloso | White amorphous phofo, lyophilized |
Ketsahalo | ≥4U/mg |
Bohloeki(SDS-PAGE) | ≥90% |
Catalase | ≤0.01% |
ATPase | ≤0.005% |
Glucose oxidase | ≤0.03% |
Cholesterol oxidase | ≤0.003% |
Lipalangoang le polokelo
Lipalangoang: Ambient
Polokelo:Boloka ho -20°C(Nako e telele), 2-8°C (nako e khutšoanyane)
E khothaletsoa tlhahlobo hapeBophelo:2 lilemo
Nalane ea nts'etsopele
E 'ngoe ea li-index tse sebelisoang tlhahlobong ea lefu la tsoekere ke glycated hemoglobin (HbA1c).Tekanyo ea HbA1c e sebelisa li-enzyme e loketse ho sebetsana le mehlala e mengata, 'me e boloka chelete e ngata.Ka hona, ke khale ho bile le pitso e matla ho tsoa ho lingaka bakeng sa nts'etsopele ea tlhahlobo ea enzyme e joalo.Ka hona, re thehile tlhahlobo e ncha re sebelisa "mokhoa oa dipeptide".Ka ho khetheha, re fumane "Fructosyl-peptide Oxidase" (FPOX) e ka sebelisoang e le enzyme bakeng sa tlhahlobo ena.Sena se nolofalitse katleho ea rona ho fihlelleng la pele lefats'eng ka ho etsa bonnete ba tlhahlobo ea enzyme ea HbA1c."Mokhoa ona oa dipeptide" o sebelisa Protease (Proteolytic enzyme) ho senya HbA1c maling, ebe o lekanya maemo a li-dipeptide tse saccharified tse hlahisoang ka FPOX.Mokhoa ona o kopane le kamohelo e ntle haholo ka lebaka la melemo ea ona ea ho ba bonolo, e theko e tlase ebile e potlakile, mme mochini oa ho metha oa HbA1c o sebelisang FPOX joale o se o sebelisoa lefatšeng ka bophara.