Cimetidine(51481-61-9)
Tlhaloso ea Sehlahisoa
● Cimetidine e na le ts'ireletso le ts'ireletso ho lefu la mala le senyang le bakoang ke ho halefisoa ke lik'hemik'hale, hape e na le katleho e kholo khatellong ea maikutlo ea seso sa ka mpeng le mali a tsoang ka maleng.
● Cimetidine ke histamine H2 receptor impedant, haholo-holo e sebelisetsoang ho thibela secretion ea acid ea gastric, e ka thibelang haholo ho hlahisa acid ea basal le nocturnal gastric acid, hape e thibela secretion ea gastric acid e bakoang ke histamine, fractional peptide gastrin, insulin le lijo tse susumetsang, le ho etsa hore ho be joalo. acidic hanyane.Cimetidine e na le ts'ireletso le ts'ireletso ho gastritis e senyang e bakoang ke ho hlohlelletsa lik'hemik'hale, hape e na le katleho e kholo khatellong ea seso sa ka mpeng le mali a tsoang ka mpeng.
●Boemo ba Boleng: USP
Ntho | Standard | Sephetho |
Ho bonahala | E tšoeu kapa e batla e le Crystalline Powder e sa nkheng, tatso e babang | Confbnn |
Boitsebiso | ||
A:(IR) | E lumellana le USP Cimetidine RS | Ikamahanya |
B: (UV) | E lumellana le USP Cimetidine RS | Ikamahanya |
Assay (e baloang ka motheo o omisitsoeng) | 98.0-102.0% | 99.9% |
Litšila | ||
Mesaletsa ha e tuka | NMT 0.2% | Ikamahanya |
Litšepe tse boima | NMT 20ppm | Ikamahanya |
Litšila tsa lintho tse phelang | Tšilafalo efe kapa efe ea Motho ka Mong NMT 0.2% | NMT 0.2% |
Kakaretso ea litšila NMT 1.0% | NMT 1.0% | |
Sebaka se qhibilihang kapa Mocheso | 139-144 °C | 141-143*C |
Tahlehelo ka ho omisa | NMT 1.0% | 0.22% |
Li-solvents tse setseng (ethanol) | NMT 0.5% | NMT 0.5% |